RaySense:
Continuous, objective UV and light exposure data for clinical trials
Ennova Health 2023 Winner of IoT Category in e-Health, Wearables and Robotics
RaySense provides sponsors with continuous measurement of real-world light exposure in clinical trials, delivering fidelity that has not previously been possible. UV exposure is the most impactful environmental factor in photosensitive disease research, yet it remains the most poorly measured confounding variable in clinical trials. A small, discreet design combined with flexible wearing options ensures correct anatomical positioning without participant burden.
Isolate drug efficacy from environmental noise
Versatile and comfortable
Scratching is more complex than a binary yes/no. ScratchSense captures seven dimensions of each scratch event, including intensity (Hz), force (N), amplitude (cm), duration, and whether nails were used, giving you endpoints that reflect the full clinical picture.
Accurate, multi-spectrum data
Measures UVB (erythemal weighted, 280-400 nm) and UVA alongside RGB and infrared light across 12 channels, plus flicker and artificial light detection. 13 optical channels in total, each individually calibrated.
Tailored spectrum response
Using atmospheric models and 13 individually measured optical channels, RaySense can provide modelled spectrum response curves tailored to mimic those of specific dermatoses. Dose thresholds and participant notifications are configurable per protocol.
Real-time dose monitoring
Configurable dose thresholds trigger participant notifications when UV limits are approached. Daily and weekly dose graphs are available in the app. Optional real-time UV Index display keeps participants informed throughout the study.
Enable High-Quality Data Capture
Flexible wearing options
Available as a finger ring (16 sizes), wristband, clip with rubberised grip, or pendant necklace. Flexible wearing positions ensure the sensor is correctly placed for the indication under study.
Real-time data sync
Sensor data is sent to the participant's smartphone via Bluetooth Low Energy and processed through Stingray Observatory for secure, audit-ready logging.
Compliance verification
A proximity sensor and skin temperature sensor detect whether the optical sensors are covered and whether sampling is valid. The 6-axis accelerometer monitors wearing behaviour and flags invalid readings automatically.
Personalised push notifications
Alerts participants as they approach protocol-defined UV dose thresholds. Configurable per study. Daily and weekly dose graphs provide a visual record of cumulative exposure.
Diego Herrera Egea
Director of Clinical Data & Digital Innovation Almirall
Sun exposure: the confounding variable rarely measured
Dermatological Research
Atopic Dermatitis, Psoriasis, Eczema, Rosacea, PLE, Solar Urticaria. UV directly modulates disease severity, confounding efficacy endpoints for topical and systemic therapies. Seasonal variation adds uncontrolled noise.
Phototherapy Trials
Vitiligo, Atopic Dermatitis, Psoriasis, PLE, Mastocytosis. The efficacy of phototherapy depends on precise UV dosing. Uncontrolled ambient UV exposure between clinic sessions directly impacts outcomes and makes it difficult to assess the true dose-response relationship.
Melanoma and Skin Cancer Trials
UV is the primary environmental risk factor for skin cancer. Unmeasured exposure complicates safety monitoring and confounds the analysis of tumour recurrence across treatment arms.
Autoimmune Photosensitivity
Lupus, Sjogren's syndrome. Photosensitivity prevalence is as high as 83% in Lupus patients. UV exposure can trigger both cutaneous lesions and systemic flares, representing a direct threat to trial validity.
Erythropoietic Protoporphyria (EPP)
Monitor light sensitivity to measure treatment response and verify that patients remain within safe exposure limits throughout the study period.
Xeroderma Pigmentosum (XP)
Collect objective exposure data while verifying that participants remain within protocol-defined UV limits throughout the study.
Immunosuppressant Therapy
Beyond increasing long-term cancer risk, immunosuppressants can act as photosensitising agents. Skin cancer risk can be up to 65 times higher in immunosuppressed patients. In Australia, up to 70% of fair-skinned transplant recipients develop skin cancer within 20 years.
Photosensitising Medications
Certain antibiotics, NSAIDs, and diuretics can induce photosensitivity, leading to unexpected adverse events that mimic side effects of the investigational product and confound safety data. Objective UV measurement separates drug effect from light-induced effect.
Designed for Comfort and Durability
Extended battery life
Operates for approximately two months per charge (configuration dependent), covering most study periods without interruption. Charges via USB-C.
13-channel optical sensor
13 individually calibrated optical channels covering UVB (280-400 nm, erythemal weighted), UVA, RGB and infrared (400-1050 nm, 12 channels), plus flicker and artificial light detection. Spectrum response curves can be tailored to specific dermatoses.
Real-time, accurate data
Dynamic sampling with averaged or spot UVI, RGB and infrared logging. Optional real-time UV Index display in the app. Daily and weekly dose graphs configurable per study.
Durable and user-friendly design
Constructed with anodised 6061 aluminium housing, IP68 rated, and easy to clean.
Bluetooth connectivity
Bluetooth Low Energy with a range of approximately 5 m. Data syncs automatically to the native Android and iOS app. Optional wired data download available via the charger.
Compliance verification
A proximity sensor and skin temperature sensor detect whether optical sensors are covered and whether sampling is valid. The 6-axis accelerometer monitors wearing behaviour and flags invalid data automatically.
Advancing Clinical Research with a Unified Sensor Portfolio
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FAQ
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Ready to add objective UV data to your trial?