Increase Engagement with our ePRO Software

Empower patients with our all-in-one ePRO Software through gamification elements, voice recordings, reminders, and an extensive suite of 20+ features crafted to minimize dropouts and motivate users.

Trusted by

Engaged Patients, Higher Retention

Improve Patient Experience

Trial Online ePRO Software is an easy to use app designed for a better patient experience throughout the study. Patients feel supported at every stage, benefiting from visit and treatment reminders, informative guidance alerts, and seamless progress tracking.

Boost Patient Retention
& Compliance

Compliance and progress efforts are celebrated on Trial Online! Our ePRO Software embraces gamification elements to make the patient journey engaging and rewarding. As questionnaires are completed and milestones are achieved, we celebrate by awarding trophies and badges as tokens of the user's success.

Enhance Data Quality

Ensure high-quality exhaustive data collection and analysis at any point in the study with effortless questionnaires, event scheduling, compliance tracking, treatment management, wearable integrations, and real-time monitoring.

Powerful Features

Study Dashboard

Get a direct overview of study performance, progress, and compliance. Take actions based on real-time statistics.

BYOD & Device Provision

Use the ePRO Software on patient's device, web or a provisioned device by Replior.

Reminders and Notifications

Schedule and send reminders and
notifications for pending tasks or upcoming visits.

Questionnaires and eDiaries

Collect ad-hoc data from patients, such as medication intake and adverse events. Get reviews by the Investigator or CRA.


Measure data and identify trends in patient or treatment development over time using advanced program calculations.


Configure treatment schedules and provide how-to guiding information to patients.


Award patients with trophies and badges when they complete tasks and motivate them with progress and compliance status bars.


Connect the ePRO to Trial Online EDC, Virtual Visits or eConsent or to your study-specific vendor systems such as RTSM or wearable devices.

Language support

Support for over 40 languages for patients, with additional languages added upon request.

Voice Recording

Allow patients to use voice recording as a memory note to remember how they felt at a point in the study.

Patient groups

Enrol patients into different groups to enable group-specific tasks.


Multiple export options are available for data extraction, including audit logs, notifications, and questionnaire exports.

Case Studies

Case study 1

Phase IV study

97% Patient retention

In a phase IV biologic study with 9 PROs to be completed at each patient visit, patient retention increased from 90% in a previous study to 97% with Trial Online ePRO Software.

Case study 2

Phase IV study

19% Increase in retention

A second 2 active treatments phase IV study with 4 PROs to be completed at each patient visit saw patient retention spike from 56% to 75% with Trial Online ePRO.

Case study 3

Phase Ill study

In a phase III study with an average population of 69 years old who completed their eDiary on Trial Online ePRO, having the paper diary version as back up, we observed that:

of patients completed the study


of total patient visits (622 visits) were completed


of patients installed the ePRO app


diary completion between eDiary and paper version


Integrate Trial Online ePRO

Trial Online ePRO Software integrates with various partners based on the unique requirements of each clinical trial, facilitating comprehensive patient data collection. By linking your specific Electronic Data Capture (EDC) or Randomization and Trial Supply Management (RTSM) system to Trial Online, you can streamline the flow of clinical trial data.

Trusted by customers, loved by users

"Introducing gamification with Trial Online has improved the satisfaction of our patients and therefore increased the robustness of the data base."
Diego Herrera Egea
Senior Leader, Clinical Data & Information Management
"Partnering with Replior has always been easy! Over the course of our studies, we have developed a friendly collaboration based on trust."
Cécile Paquet Luzy
MSc Head of Clinical Science

See the power of Trial Online

Why you should book a demo:

Customized experience:

See how our ePRO software works in a real-world context that's relevant to your organization.

Expert guidance:

Our experts will guide you through all the features and functionalities of our platform.

Assess compatibility:

Understand how our ePRO software can integrate with your existing systems and processes.

Clarify your doubts:

Use this opportunity to ask questions and clarify any doubts you may have.

Request your live demo

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