Digital Endpoints:

Objective Data for Smarter Clinical Trials

Patient diaries tell you how participants felt. Replior’s clinical-grade ring sensors tell you what actually happened. ScratchSense and RaySense capture continuous, objective data that no self-report instrument can replicate.

Modern clinical trials demand data that goes beyond what patients can recall or record. Replior’s sensor platform delivers exactly that: objective, continuous measurements from purpose-built clinical devices that complement patient-reported outcomes.

ScratchSense measures nocturnal scratch activity and sleep quality in itch-indication trials. RaySense measures real-world UV, visible, and infrared light exposure in dermatology and photosensitive disease studies. Both run on the same validated ring platform, backed by a compliance-grade sensor backend built for clinical-trial audit requirements.

We believe the future of clinical research lies in achieving a balance between patient-reported outcomes and objective sensor data. Listening to how patients feel and experience treatment remains essential, but combining these insights with unbiased, device-reported data allows researchers to gain a fuller, more reliable understanding of patient health and trial outcomes.

Explore Our Digital Endpoints

RaySense

UV, visible, and infrared light exposure monitoring

RaySense is a clinical-grade ring sensor that measures continuous real-world exposure to UV-B, UV-A, visible light, and infrared radiation. In dermatology trials, photosensitive disease studies, and cosmetics research, light exposure is the most consequential uncontrolled variable. RaySense turns it into a measurable, audit-ready covariate.

ScratchSense

Nocturnal scratch and sleep monitoring

ScratchSense is a clinical-grade ring sensor that objectively quantifies scratch behaviour and sleep quality in itch-indication trials. It captures what patient diaries cannot: continuous nocturnal data on scratch events, sleep efficiency, and wake after sleep onset, validated against IR video ground truth. Built for dermatology studies where itch is the primary endpoint.

Why Choose Replior Digital Endpoints?

Consumer wearables were not built for clinical evidence. Replior’s sensors are. Every design decision, from the ring form factor to the compliance-grade backend, is made for trials where data integrity, long-term wear compliance, and regulatory defensibility are non-negotiable.

Clinical-grade accuracy:

Validated against objective ground truth, not just self-report comparison. ScratchSense targets greater than 95% average scratch-tracking accuracy.

Designed for long-term wear:

The ring form factor is comfortable for extended wear across studies lasting weeks to months. Patients who find the device uncomfortable remove it. Replior's design is built so they do not.

Compliance-grade data provenance:

Stingray Observatory, Replior's sensor backend, logs every data receipt, processing step, and configuration change. Sensor data is as auditable as your EDC data.

Purpose-built for clinical trials:

Every sensor in the Replior platform is designed specifically for clinical use, not repurposed from consumer technology. Validated methodology, traceable data, and a backend built to satisfy sponsor audits and regulatory inspections.

Ready to add objective endpoints to your trial?